A friend of mine is 'bio hacker'; he works with different microbiological organisms to learn about them and build better ones with specific traits. This article describes it better than I can: http://www.nature.com/news/2010/101006/full/467650a.html
I'm an amateur bladesmith. This guy posts regularly on one of the forums I participate in. He's chronicled his research there in very accessible, but rich detail. Really brilliant stuff (from my layman perspective).