If you use google as your homepage, you can change the address to something like that:

http://www.google.com/webhp?complete=0&hl=en

You can add as many parameters as you want [1]. I use complete=0 to disable suggestions (I don't need/want them) and hl=en to force the interface language to be in english

[1] http://yoast.com/wp-content/uploads/2007/07/google-url-param...