Either San Francisco proper (especially SOMA), or around Palo Alto / Mountain View would be my suggestions.
Most of the meetup type events I've been to have been in SF. Lots of startups are based in SF too (of the winter 2008 YC companies I think only a handfull are still in the valley, the rest are in SF or elsewhere).
Startups seem to congregate in or near SOMA in particular. The three SF JS meetups I've been to have been in SOMA: Hi5, SlideShare, and Serious Business. Also: Twitter (and their old office's new residents, Get Satisfaction), Engine Yard, and numerous YC companies like Disqus, SnapTalent, Xobni, Justin.TV. And lots of others I would probably know about if I actually lived up there.
But the valley is great too. Of course there's lots of startups there as well. Palo Alto and Mountain View are both quite nice. But be careful because there are lots of boring suburban and strip mall type areas in Silicon Valley.
Most of the meetup type events I've been to have been in SF. Lots of startups are based in SF too (of the winter 2008 YC companies I think only a handfull are still in the valley, the rest are in SF or elsewhere).
Startups seem to congregate in or near SOMA in particular. The three SF JS meetups I've been to have been in SOMA: Hi5, SlideShare, and Serious Business. Also: Twitter (and their old office's new residents, Get Satisfaction), Engine Yard, and numerous YC companies like Disqus, SnapTalent, Xobni, Justin.TV. And lots of others I would probably know about if I actually lived up there.
But the valley is great too. Of course there's lots of startups there as well. Palo Alto and Mountain View are both quite nice. But be careful because there are lots of boring suburban and strip mall type areas in Silicon Valley.