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Wow, that's not great. I take it these are meant to be used as a stopgap before an actual transplant?


Not always, some are”destination” therapy meaning no transplant planned in the immediate future.

https://my.clevelandclinic.org/health/treatments/17192-left-...


That's an LVAD, though -- isn't that an entirely different beast than an artificial heart, with a different use case?


It's still typically a massive change in quality of life. The left ventricle is what feeds your entire body blood; the right ventricle only feeds the lungs. When the left ventricle fails, blood backs up and starts overflowing into the lung space in addition to the rest of your body slowly suffocating. It's exceptionally unpleasant.

The right ventricle is usually in much better shape so an LVAD can be almost like having a functioning transplant, except that there's a big wire going out of your chest/neck (which is a constant infection risk and can't really get wet) and you're now battery-powered.

Any kind of heart transplant comes with huge problems, even besides the immunosupressants etc. The nerves don't reconnect, so the heart doesn't respond to commands to speed up. It makes any kind of exertion difficult and unpleasant. Diet is critical, clots are a constant fear, etc. By the time you get a transplant you've usually spent a while with insufficient bloodflow, and your organs have been slowly dying.

It's nothing short of incredible that people can get 20+ years out of transplants. The deck is stacked against us hard.


Artificial heart is kind of a non-specific term. It covers anything from LVAD, LBAD and RVAD together, ECMO or biventrivular vad. So depends on what you’re specifically referring to but lvad is the most common of those.


Fair enough. I'm in no way experienced in the medical field. I would have told you I thought an artificial heart was a complete heart replacement, just like a full transplant but with a mechanical device instead. TIL.


LVAD goes for 5 years


More like 10 and more now, 5 years was the stuff we were making in the 90s and early 2000s.


Yes, syncardia is primarily used as a bridge to transplant.


Yea; it's a stopgap solution. The pump is in a backpack so it's not perfect for mobility.


LVADs are implanted in your chest. Blood doesn't leave your body, but do they have external batteries. You have a wire coming out of your chest (or neck/head, sometimes) which is a constant infection worry. AFAIK the only external pumps are like, countertop kind of things.

They're ideally a stopgap, but even still it's typically a massive change in quality of life. The left ventricle is what feeds your entire body blood; the right ventricle only feeds the lungs. When the left ventricle fails, blood backs up and starts overflowing into the lung space. It's exceptionally unpleasant. The right ventricle is usually in much better shape so an LVAD can be almost like having a functioning transplant except for the risk of infection.


Well, half of your hearth failing being "exceptionally unpleasant" is not a surprise.

Anyways, wouldn't it be feasible to use wireless power transfer?


It is, and it has even been done. One large limitation is that it's not a great idea to have batteries inside the body. An LVAD is intrinsically liquid-cooled; batteries are not. Ruggedly encapsulating a battery means it is fairly well-insulated and can get warm. Batteries also fail pretty unpredictably- they're fundamentally dozens of square feet of very thin film, and it's very difficult to ensure that every battery is perfect. But again, it has been done.

Implanting a couple medium-size batteries and the circuitry+magnet for wireless charging is pretty robust to failure, but consider actually making that decision for yourself. You're already accepting huge restrictions, so is the wire that much of an extra burden?

Realistically, if the LVAD loses power, you're dead. It's not like suffocating; without bloodflow (even blood without oxygen!) your brain will die in about two minutes. Chest compressions probably won't even help. You got the LVAD because your heart couldn't pump, and chest compressions will not force blood through the LVAD. Even if this happens in the emergency room your odds are not good. Cutting open a chest to hand-crank a human is not easy. Pulling an ECMO machine and inserting the massive catheters is not easy. You might die while the machine is still rolling towards you.


I thought your real heart kind of recovered a bit since it wasn't going through the workload.




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