Yep, regular VMs where you basically only care about the CPU and RAM are easy, provided nothing in the VM is trying to not run in a VM. USB and network emulation used to be jagged edges, but that was fixed. VirtualBox was my go-to. It never had great GPU support, but the rest was easy.

I'm pretty sure there are solutions to assign an entire GPU to a VM, which ofc is only useful if you have multiple. But those are specialized.