You don't need to "know Lisp" in the sense of being proficient, but you need to be familiar with s-expressions. Once you grok s-expressions, the rest is "just" grokking a bunch of functional idioms not specific to Clojure.
Actually if you're familiar with Haskell then Clojure idioms should be more familiar to you. Clojure's datatypes are (almost all) immutable, driving it towards a lot of functional idioms you see in such as Haskell or maybe Scala.
Immutability is not the whole story. There is also parametric polymorphism, algebraic data types and pattern matching (best case analysis tool ever), type classes for type constructors (not just types), etc.
Of course. That said, Clojure doesn't have those, given that it has a dynamic type system and destructuring instead of pattern matching (not as clean, IMHO), so a comparison to Haskell in this respect is less useful.
Actually if you're familiar with Haskell then Clojure idioms should be more familiar to you. Clojure's datatypes are (almost all) immutable, driving it towards a lot of functional idioms you see in such as Haskell or maybe Scala.