I've been thinking about putting together a blog post explaining how I use it for my book projects... however the short of it is: org-export.
I can map out my book chapters and sections in a typical tree. I use :noexport: for sub-trees in which I keep notes and errata. Since I use LaTeX I can give my documents some more direct formatting control using #+BEGIN_LATEX blocks (which I have found useful for adding a title page, controlling flow positioning of tables, etc). And I've written a little elisp to hook in some functions which run the texi2pdf program on my exported output automatically.
The nice thing is that I don't have to worry about typesetting until much later. I can just focus on the text, structure and flow. I can have my notes inline. It's really quite a nice setup.
Please do write this post. There's not enough examples of working setups for publishing with org mode; your experience will be helpful to many (myself included).