I'd also make sure that you honestly ask yourself the following question, when it comes to this relocation / radical burn rate reduction issue:
Can I somehow make more money with what I (we) am about to create and stay where I am (or US)?
Sure these places have cheap rent, but you also leave all your social ties behind and will be limited to a particular subset of the social fabric (expats, most likely, that either teach English or are avoiding something important by coming there). It's also distracting by being elsewhere, though often in a good way.
Can I somehow make more money with what I (we) am about to create and stay where I am (or US)?
Sure these places have cheap rent, but you also leave all your social ties behind and will be limited to a particular subset of the social fabric (expats, most likely, that either teach English or are avoiding something important by coming there). It's also distracting by being elsewhere, though often in a good way.